Physalin A

• CAT Number: I043957
• CAS Number: 23027-91-0
• Molecular Formula: C28H30O10
• Molecular Weight: 526.53
• Purity: ≥95%
• Synonyms: (1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R)-5,7,18-trihydroxy-1,14,21-trimethyl-25-methylidene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,11-diene-13,19,24,27-tetrone
• IUPAC Name: 5,7,18-trihydroxy-1,14,21-trimethyl-25-methylidene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,11-diene-13,19,24,27-tetrone
• InChI: InChI=1S/C28H30O10/c1-12-21(32)36-17-11-23(12,2)19-20(31)27(35)18-14(24(3)13(10-15(18)29)6-5-7-16(24)30)8-9-26(34)22(33)37-25(17,4)28(19,26)38-27/h5,7,10,14-15,17-19,29,34-35H,1,6,8-9,11H2,2-4H3
• InChIKey: VELDODQHYQSJOF-UHFFFAOYSA-N
• SMILES: CC12CC(C3(C45C1C(=O)C(O4)(C6C(CCC5(C(=O)O3)O)C7(C(=CC6O)CC=CC7=O)C)O)C)OC(=O)C2=C

Physalin A（Cat No.:I043957）is a naturally occurring seco-steroidal compound isolated from Physalis species, known for its diverse pharmacological activities. It exhibits potent anti-inflammatory, antitumor, immunomodulatory, and antiparasitic properties by modulating key cellular pathways such as NF-κB, STAT3, and MAPK. Physalin A has been shown to induce apoptosis, inhibit cancer cell proliferation, and suppress inflammatory cytokine production. Its complex structure contributes to its bioactivity, making it a valuable lead compound in drug discovery. Researchers study Physalin A for its therapeutic potential in cancer, autoimmune diseases, and infectious disease treatment.