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PHTPP

PHTPP

  • CAT Number: I010602
  • CAS Number: 805239-56-9
  • Molecular Formula: C20H11F6N3O
  • Molecular Weight: 423.3
  • Purity: ≥95%
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PHTPP (CAT: I010602) is a selective estrogen receptor beta (ERβ) antagonist. It exhibits a 36-fold selectivity for ERβ over ERα, which are two subtypes of estrogen receptors. PHTPP demonstrates full antagonism at ERβ in a cotransfection assay using human endometrial cancer cells (HEC-1), while showing minimal effects on ERα. This selectivity makes PHTPP a valuable tool for studying the specific functions and signaling pathways mediated by ERβ.

Catalog Number I010602
CAS Number 805239-56-9
Molecular Formula

C20H11F6N3O

Purity 95%
Target Estrogen/progestogen Receptor
Solubility Soluble to 33 mM in DMSO and to 100 mM in ethanol
Storage Store at RT
InChIKey AEZPAUSGTAHLOQ-UHFFFAOYSA-N

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