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PF-03463275

PF-03463275

  • CAT Number: I008654
  • CAS Number: 1173177-11-1
  • Molecular Formula: C19H22ClFN4O
  • Molecular Weight: 376.86
  • Purity: ≥95%
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PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, the GlyT1 glycine transporter, developed for potential anti-schizophrenia activity.

Catalog Number I008654
CAS Number 1173177-11-1
Synonyms

PF-03463275; PF03463275; PF 03463275; KB-79869; KB 79869.;N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide

Molecular Formula

C19H22ClFN4O

Purity 95%
Target CNS-Penetrant Inhibitor
Solubility Soluble in DMSO
Storage 0 - 4 °C for short term, or -20 °C for long term
InChI InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?
InChIKey KYLOBHXXQOZRKK-YIONKMFJSA-N
SMILES O=C(C1=CN(C)C=N1)N(CC2=CC=C(F)C(Cl)=C2)CC3[C@@]4([H])CN(C)C[C@@]34[H]

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