PARP14 inhibitor H10

  • CAT Number: I017973
  • CAS Number: 2084811-68-5
  • Molecular Formula: C₂₄H₂₇N₇O₇S
  • Molecular Weight: 557.58
  • Purity: ≥95%
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PARP14 inhibitor H10 (CAT: I017973) is a potent and selective inhibitor of PARP14, also known as vault poly(ADP-ribose) polymerase (VPARP). PARP14 is a member of the poly(ADP-ribose) polymerase (PARP) family of enzymes that play a role in DNA damage repair and transcriptional regulation. H10 specifically targets PARP14 and inhibits its enzymatic activity, which is involved in various cellular processes, including immune response modulation and inflammatory signaling pathways. By blocking PARP14, H10 has the potential to regulate these processes and has been studied as a potential therapeutic agent for immune-related and inflammatory diseases.

Catalog Number I017973
CAS Number 2084811-68-5
Molecular Formula

C₂₄H₂₇N₇O₇S

Purity 95%
Reference

[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.

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