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Paprotrain

Paprotrain

  • CAT Number: I010679
  • CAS Number: 57046-73-8
  • Molecular Formula: C16H11N3
  • Molecular Weight: 245.3
  • Purity: ≥95%
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Paprotrain（Cat No.:I010679） is an inhibitor of cell permeable kinesin MKLP-2. It inhibits the ATPase activity of MKLP-2 with IC50 value of 1.35μM and Ki value of 3.36μM. It also has a moderate inhibitory effect on DYRK1A with IC50 value of 5.5μM.

Catalog Number I010679
CAS Number 57046-73-8
Molecular Formula

C16H11N3

Purity 95%
Target ATPase
Solubility Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage 2-8°C
IUPAC Name (Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile
InChI InChI=1S/C16H11N3/c17-9-13(8-12-4-3-7-18-10-12)15-11-19-16-6-2-1-5-14(15)16/h1-8,10-11,19H/b13-8+
InChIKey YMYYQRZCCKBFBE-MDWZMJQESA-N
SMILES C1=CC=C2C(=C1)C(=CN2)C(=CC3=CN=CC=C3)C#N

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