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Paliperidone Palmitate

Paliperidone Palmitate

  • CAT Number: R054433
  • CAS Number: 199739-10-1
  • Molecular Formula: C39H57FN4O4
  • Molecular Weight: 664.907
  • Purity: ≥95%
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<p>
<span style="font-size:12px;"><span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;">Paliperidone Palmitate (CAS&nbsp;199739-10-1) is an&nbsp;impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications.&nbsp;</span><span style="font-family: Arial, sans-serif;">Intramuscular p</span><span style="font-family: arial, helvetica, sans-serif;">aliperidone palmitate</span><b style="color: rgb(0, 0, 0); font-family: Arial, sans-serif; font-size: 13px;">&nbsp;</b><span style="font-family: Arial, sans-serif;">is a long-acting, atypical antipsychotic that is indicated&nbsp;</span><span style="font-family: Arial, sans-serif;">in the US for the acute and maintenance therapy of adult patients with schizophrenia.</span></span></span></p>

Catalog Number R054433
CAS Number 199739-10-1
Molecular Formula

C39H57FN4O4

Purity 95%
Storage Desiccate at RT
Overview of Clinical Research

<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Paliperidone Palmitate is&nbsp; a dopamine D2 receptor antagonist and a serotonin 2 receptor antagonist. It is preregistrated for Schizophrenia (Treatment-experienced) in European Union (IM).</span></span></span></p>

IUPAC Name [3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl] hexadecanoate
InChI InChI=1S/C39H57FN4O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18-36(45)47-34-17-16-24-44-38(34)41-29(2)32(39(44)46)23-27-43-25-21-30(22-26-43)37-33-20-19-31(40)28-35(33)48-42-37/h19-20,28,30,34H,3-18,21-27H2,1-2H3
InChIKey VOMKSBFLAZZBOW-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCCCCC(=O)OC1CCCN2C1=NC(=C(C2=O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F)C
Reference

<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Nussbaum, Abraham M., and T. Scott Stroup. &quot;Paliperidone palmitate for schizophrenia.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Cochrane Database of Systematic Reviews</i>&nbsp;6 (2012).<br />
2.Hoy, Sheridan M., Lesley J. Scott, and Gillian M. Keating. &quot;Intramuscular paliperidone palmitate.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">CNS drugs</i>&nbsp;24.3 (2010): 227-244.</span></span></span>

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