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PAF C-18:1

PAF C-18:1

  • CAT Number: R065922
  • CAS Number: 85966-90-1
  • Molecular Formula: C28H56NO7P
  • Molecular Weight: 549.7
  • Purity: ≥95%
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PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 (Item No. <span class=/itemid/>60900</span>) and PAF C-18 (Item No. <span class=/itemid/>60910</span>) in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration. PAF C-18:1 activates the PAF receptor and has been used in antibody binding experiments to determine the importance of an acyl linkage at the <em>sn</em>-2 position for recognition at this receptor.

Catalog Number R065922
CAS Number 85966-90-1
Molecular Formula

C28H56NO7P

Purity 95%
Storage -20°C
InChI InChI=1S/C28H56NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h13-14,28H,6-12,15-26H2,1-5H3/b14-13-/t28-/m1/s1
InChIKey ZBOQHUSCQCEBGK-JLRCLJKCSA-N
SMILES CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCC/C=CCCCCCCCC)=O
Reference

1.Carolan, E.J. and Casale, T.B. Degree of platelet activating factor-induced neutrophil migration is dependent upon the molecular species. Journal of Immunology 145, 2561-2565 (1990).

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