p38α inhibitor 1

• CAT Number: I019450
• CAS Number: 1034189-82-6
• Molecular Formula: C₂₂H₂₆F₂N₄O₂
• Molecular Weight: 416.46
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: 5-(2,4-difluorophenoxy)-N-[2-(dimethylamino)ethyl]-1-(2-methylpropyl)indazole-6-carboxamide
• InChI: InChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)
• InChIKey: IFGWYHGYNVGVRB-UHFFFAOYSA-N
• SMILES: CC(C)CN1C2=CC(=C(C=C2C=N1)OC3=C(C=C(C=C3)F)F)C(=O)NCCN(C)C

p38α inhibitor 1（Cat No.:I019450） is a compound identified as a p38α inhibitor in a patent (WO 2008076265 A1). It specifically targets p38α, a member of the p38 MAPK family involved in cellular signaling and inflammation. The compound’s exact chemical structure and characteristics are not provided in the given information. However, its designation as a p38α inhibitor suggests its potential for modulating p38α activity, which may have implications in various physiological and pathological processes.

Reference

[1]. Baker W, et al. Monophosphates as mutual prodrugs of anti-inflammatory signal transduction modulators (aistm’s) and β-agonists for the treatment of pulmonary inflammation and bronchoconstriction. WO 2008076265 A1.