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Oxeladin citrate

Oxeladin citrate

  • CAT Number: I003917
  • CAS Number: 52432-72-1
  • Molecular Formula: C26H41NO10
  • Molecular Weight: 527.6
  • Purity: ≥95%
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Oxeladin citrate(cas# 52432-72-1) is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies.
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Catalog Number I003917
CAS Number 52432-72-1
Synonyms

Oxeladin citrate; 2-(2-Diethylaminoethoxy)ethyl α,α-diethylphenylacetate

Molecular Formula

C26H41NO10

Purity 95%
Solubility 10 mM in H2O
Storage -20°C
Related CAS 468-61-1(free base)
InChI 1S/C20H33NO3.C6H8O7/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4;7-3(8)1-6(13,5(11)12)2-4(9)10/h9-13H,5-8,14-17H2,1-4H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChIKey KVKJFNUGVOFNGU-UHFFFAOYSA-N
SMILES CCC(CC)(C1=CC=CC=C1)C(=O)OCCOCCN(CC)CC.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Reference

1: El-Gindy A. High performance liquid chromatographic determination of oxeladin
citrate and oxybutynin hydrochloride and their degradation products. Farmaco.
2005 Aug;60(8):689-99. PubMed PMID: 16023117.
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2: Lartigue-Mattei C, Galmier MJ, Chabard JL, Beyssac E, Aiache JM. Determination
of oxeladin in human plasma by gas chromatography–mass spectrometry. Biomed
Chromatogr. 1995 Jan-Feb;9(1):32-5. PubMed PMID: 7734931.
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3: Knopp C, Korsatko W. [Determination of oxeladin citrate in drug combinations].
Pharmazie. 1982 Jan;37(1):76-7. German. PubMed PMID: 7071116.

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4: Salvesen B, Haugland T. Determination of oxeladin in human sera by gas–liquid
chromatography with thermionic detection. J Chromatogr. 1981 Oct 9;225(2):463-8.
PubMed PMID: 7298782.

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5: Takagi K, Yuizono T, Kasé Y. [On the site of antitussive action of
2-(2-diethylaminoethoxy)ethyl alpha,alpha-diethylphenylacetate (Oxeladin)].
Yakugaku Zasshi. 1967 Aug;87(8):898-906. Japanese. PubMed PMID: 5625837.
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6: OZAWA H, FUKUDA H, OTSUKI I, CHIBA S. [Antitussive activity and acute toxicity
of 2-(2-diethylamino-ethoxy)ethyl alpha,alpha-diethylphenylacetate (oxeladin)].
Yakugaku Zasshi. 1962 Sep;82:1314-7. Japanese. PubMed PMID: 13940888.

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7: DAVID A, LEITH-ROSS F, VALLANCE DK. Antitussive and other pharmacological
properties of the diethylaminoethoxyethyl ester of alpha
alpha-diethylphenylacetic acid, (oxeladin). J Pharm Pharmacol. 1957
Jul;9(7):446-58. PubMed PMID: 13439531.

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