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ONO-4059 hydrochloride

ONO-4059 hydrochloride

  • CAT Number: I001695
  • CAS Number: 1439901-97-9
  • Molecular Formula: C25H23ClN6O3
  • Molecular Weight: 490.94
  • Purity: ≥95%
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ONO-4059 hydrochloride (Cat.No:I001695) is a selective inhibitor of Bruton’s tyrosine kinase (BTK). It has shown promising results in preclinical and clinical studies for the treatment of B-cell malignancies, including chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). ONO-4059 hydrochloride holds potential as a targeted therapy for BTK-driven cancers.

Catalog Number I001695
CAS Number 1439901-97-9
Molecular Formula

C25H23ClN6O3

Purity 95%
Target target:BTK.
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

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<br>[1]. Harriet S et al. A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies. Blood 2016, 127:411-419

<br>[2]. Akintunde Akinleye et al. Ibrutinib and novel BTK inhibitors in clinical development. J Hematol Oncol, 2013, 6: 59.

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