For research use only. Not for therapeutic Use.
OncoFAP (Cat No.:I043843) is a peptide designed to selectively bind to fibroblast activation protein (FAP), a cell surface protease overexpressed in many tumors, particularly in the tumor stroma. By targeting FAP, OncoFAP can enhance the delivery of diagnostic agents or therapeutic payloads directly to cancerous tissues. This peptide is used in research to explore tumor-targeted therapies, including imaging and drug delivery strategies, aimed at improving the specificity and effectiveness of cancer treatments. Its ability to bind FAP makes it a valuable tool for cancer diagnosis and targeted therapy.
| CAS Number | 2639365-69-6 |
| Synonyms | 4-[[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-8-yl]amino]-4-oxobutanoic acid |
| Molecular Formula | C21H19F2N5O5 |
| Purity | ≥95% |
| IUPAC Name | 4-[[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-8-yl]amino]-4-oxobutanoic acid |
| InChI | InChI=1S/C21H19F2N5O5/c22-21(23)8-12(9-24)28(11-21)17(30)10-26-20(33)14-6-7-25-19-13(14)2-1-3-15(19)27-16(29)4-5-18(31)32/h1-3,6-7,12H,4-5,8,10-11H2,(H,26,33)(H,27,29)(H,31,32)/t12-/m0/s1 |
| InChIKey | PNRJDKPIARNTNM-LBPRGKRZSA-N |
| SMILES | C1[C@H](N(CC1(F)F)C(=O)CNC(=O)C2=C3C=CC=C(C3=NC=C2)NC(=O)CCC(=O)O)C#N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
