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Omeprazole-d3

Omeprazole-d3

  • CAT Number: R067094
  • CAS Number: 934293-92-2
  • Purity: ≥95%
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Omeprazole-d<sub>3</sub> is intended for use as an internal standard for the quantification of omeprazole (Item No. <span class=/itemid/>14880</span>) by GC- or LC-MS. Omeprazole is a selective and irreversible inhibitor of the gastric H It is a racemic mixture of two enantiomers, S-omeprazole (esomeprazole magnesium; Item No. <span class=/itemid/>17326</span>) and R-omeprazole (sodium salt) (Item No. <span class=/itemid/>18874</span>), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion. Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.

Catalog Number R067094
CAS Number 934293-92-2
Purity 95%
Storage Room temperature
Reference

1.Smolka, A.J.,Goldenring, J.R.,Gupta, S., et al. Inhibition of gastric H,K-ATPase activity and gastric epithelial cell IL-8 secretion by the pyrrolizine derivative ML 3000. BMC Gastroenterol. 4(4), 1-11 (2004).

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