ODQ

• CAT Number: R051439
• CAS Number: 41443-28-1
• Molecular Formula: C9H5N3O2
• Molecular Weight: 187.158
• Purity: ≥95%
• Target: Nitric Oxide
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at +4C
• IUPAC Name: [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
• InChI: InChI=1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H
• InChIKey: LZMHWZHOZLVYDL-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)N=CC3=NOC(=O)N23

ODQ (CAT: R051439), 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, is a potent and selective inhibitor of soluble guanylyl cyclase (sGC). It is widely used in experimental research to investigate the role of nitric oxide (NO) signaling pathways. By inhibiting sGC, ODQ blocks the conversion of guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP), affecting vasodilation and various physiological processes. ODQ’s action has implications in cardiovascular and neuronal research, helping elucidate NO’s influence on cellular responses, neurotransmission, and vascular tone regulation. Its use provides insights into cyclic nucleotide signaling, making ODQ a valuable tool in molecular and pharmacological investigations.