OD 36

  • CAT Number: R032873
  • CAS Number: 1638644-62-8
  • Molecular Formula: C₁₆H₁₅ClN₄O₂
  • Molecular Weight: 330.77
  • Purity: ≥95%
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OD36 is a cell permeable, highly potent, selective, and ATP-competitive inhibitor of receptor-interacting protein 2 (RIPK2, IC₅₀ = 5.3 nM).

Catalog Number R032873
CAS Number 1638644-62-8
Molecular Formula

C₁₆H₁₅ClN₄O₂

Purity 95%
Target RIPK2 inhibitor
Storage -20°C
Reference

</br>1:In vivo evaluation of [<sup>18</sup>F]FECIMBI-36, an agonist 5-HT<sub>2A/2C</sub> receptor PET radioligand in nonhuman primate. Prabhakaran J, Solingapuram Sai KK, Zanderigo F, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Tooke KI, Mintz A, Mann JJ, Kumar JS.Bioorg Med Chem Lett. 2017 Jan 1;27(1):21-23. doi: 10.1016/j.bmcl.2016.11.043. Epub 2016 Nov 16. PMID: 27889455 </br>2:PO-36 – Thrombin Inhibition Preoperatively (TIP) in early breast cancer, the first clinical trial of NOACs as an anti-cancer agent: trial methodology. Kirwan CC, Bundred NJ, Castle J, Clarke R, Dive C, Morris J, Holcombe C, Harvey JR.Thromb Res. 2016 Apr;140 Suppl 1:S189-90. doi: 10.1016/S0049-3848(16)30169-4. Epub 2016 Apr 8. PMID: 27161723 </br>3:The Bicoid class homeodomain factors ceh-36/OTX and unc-30/PITX cooperate in C. elegans embryonic progenitor cells to regulate robust development. Walton T, Preston E, Nair G, Zacharias AL, Raj A, Murray JI.PLoS Genet. 2015 Mar 4;11(3):e1005003. doi: 10.1371/journal.pgen.1005003. eCollection 2015 Mar. PMID: 25738873 Free PMC Article</br>4:Vision and eye health in children 36 to &lt;72 months: proposed data definitions. Marsh-Tootle WL, Russ SA, Repka MX; National Expert Panel to the National Center for Children’s Vision Eye Health..Optom Vis Sci. 2015 Jan;92(1):17-23. doi: 10.1097/OPX.0000000000000444. PMID: 25562477 Free PMC Article</br>5:Vision screening for children 36 to &lt;72 months: recommended practices. Cotter SA, Cyert LA, Miller JM, Quinn GE; National Expert Panel to the National Center for Children’s Vision and Eye Health..Optom Vis Sci. 2015 Jan;92(1):6-16. doi: 10.1097/OPX.0000000000000429. PMID: 25562476 Free PMC Article</br>6:Connexin 36 mediates blood cell flow in mouse pancreatic islets. Short KW, Head WS, Piston DW.Am J Physiol Endocrinol Metab. 2014 Feb;306(3):E324-31. doi: 10.1152/ajpendo.00523.2013. Epub 2013 Dec 10. PMID: 24326425 Free PMC Article</br>7:NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O.Mol Cell. 2011 Nov 18;44(4):609-20. doi: 10.1016/j.molcel.2011.08.042. PMID: 22099308 Free PMC Article</br>8:Antigen sandwich ELISA predicts RT-PCR detection of dengue virus genome in infected culture fluids of Aedes albopictus C6/36 cells. Buerano CC, Natividad FF, Contreras RC, Ibrahim IN, Mangada MN, Hasebe F, Inoue S, Matias RR, Igarashi A.Southeast Asian J Trop Med Public Health. 2008 Sep;39(5):817-21. PMID: 19058574 </br>9:Preserved vision without growth retardation after laparoscopic Roux-en-Y gastric bypass in a morbidly obese child with pseudotumor cerebri: 36-month follow-up. Leslie DB, Kellogg TA, Boutelle KN, Barnett SJ, Schwarzenberg SJ, Harrison AR, Ikramuddin S.J Pediatr Surg. 2008 Jul;43(7):e27-30. doi: 10.1016/j.jpedsurg.2008.05.001. PMID: 18639671

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