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O4I1

O4I1

  • CAT Number: I002286
  • CAS Number: 175135-47-4
  • Molecular Formula: C16H15NO2
  • Molecular Weight: 253.3
  • Purity: ≥95%
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IO4I1 is an effective Oct3 / 4 inducer. O4I1 enhanced about 2.5- and 4-fold Oct3 / 4 gene expression, increased Oct3 / 4 protein levels, and promoted Oct3 / 4-mediated transcriptional activation at concentrations of 10 μM and 20 μM, respectively.

Catalog Number I002286
CAS Number 175135-47-4
Molecular Formula

C16H15NO2

Purity 95%
Target Transcription Factors
Solubility DMSO: ≥ 38 mg/mL
Storage Room Temperature
IUPAC Name 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile
InChI InChI=1S/C16H15NO2/c1-18-15-6-4-14(5-7-15)12-19-16-8-2-13(3-9-16)10-11-17/h2-9H,10,12H2,1H3
InChIKey QJEJLARVLKHYFW-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)COC2=CC=C(C=C2)CC#N
Reference

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<br>[1]. Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015 Jun 25;58(12):4976-4983.
<br>[2]. Mrowka, et al. Method for activating OCT4 for induction of pluripotent stem cell formation. From PCT Int. Appl. (2014), WO 2014000814 A1 20140103.
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