NTNCB hydrochloride

  • CAT Number: I010516
  • CAS Number: 191931-56-3
  • Molecular Formula: C25H33N3O4S.HCl
  • Molecular Weight: 508.07
  • Purity: ≥95%
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Selective, non-peptide competitive NPY Y<sub>5</sub> antagonist. K<sub>i</sub> values are 8.0 and 16032 nM at human recombinant Y<sub>5</sub> and Y<sub>1</sub> receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D<sub>2</sub> and <span class=/’symbol/’>&alpha;</span><sub>2C</sub> receptors (K<sub>i</sub> values are 63 and 100 nM respectively).

Catalog Number I010516
CAS Number 191931-56-3
Synonyms

2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride

Molecular Formula

C25H33N3O4S.HCl

Purity 95%
Target NPY Receptors
Solubility Soluble to 100 mM in DMSO
Storage Store at RT

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