NSP-AS

• CAT Number: I045012
• CAS Number: 211106-69-3
• Molecular Formula: C28H28N2O8S2
• Molecular Weight: 584.66
• Purity: ≥95%
• Synonyms: 3-[9-[3-carboxypropyl-(4-methylphenyl)sulfonylcarbamoyl]acridin-10-ium-10-yl]propane-1-sulfonate
• InChI: InChI=1S/C28H28N2O8S2/c1-20-13-15-21(16-14-20)40(37,38)30(18-6-12-26(31)32)28(33)27-22-8-2-4-10-24(22)29(17-7-19-39(34,35)36)25-11-5-3-9-23(25)27/h2-5,8-11,13-16H,6-7,12,17-19H2,1H3,(H-,31,32,34,35,36)
• InChIKey: VYTOBATYLKBDAR-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)N(CCCC(=O)O)C(=O)C2=C3C=CC=CC3=[N+](C4=CC=CC=C42)CCCS(=O)(=O)[O-]

NSP-AS（Cat No.:I045012）is a selective fluorescent probe designed for the rapid and sensitive detection of peroxynitrite (ONOO⁻) in biological systems. Upon interaction with peroxynitrite, NSP-AS undergoes a chemical transformation that results in a significant fluorescence enhancement, enabling real-time imaging of nitrosative stress in live cells. It offers high selectivity over other reactive oxygen and nitrogen species, fast response kinetics, and low cytotoxicity. NSP-AS is widely used in studies of oxidative and nitrosative damage, particularly in inflammation, neurodegenerative diseases, and cardiovascular disorders, helping to elucidate the role of ONOO⁻ in pathological processes.