For research use only. Not for therapeutic Use.
NSC693868（Cat No.:R032971）is a small-molecule inhibitor known for its ability to disrupt the interaction between heat shock protein 90 (Hsp90) and its co-chaperone p23, thereby impairing Hsp90’s chaperone function. This disruption leads to the destabilization and degradation of Hsp90 client proteins, many of which are involved in cancer cell growth, survival, and signal transduction. NSC693868 has demonstrated antitumor activity in various cancer models by inducing apoptosis and inhibiting oncogenic pathways. It is a valuable research tool for studying chaperone-mediated protein regulation and for exploring therapeutic strategies targeting Hsp90 in oncology.
| CAS Number | 40254-90-8 |
| Synonyms | 2H-pyrazolo[4,3-b]quinoxalin-3-amine |
| Molecular Formula | C9H7N5 |
| Purity | ≥95% |
| IUPAC Name | 2H-pyrazolo[4,3-b]quinoxalin-3-amine |
| InChI | InChI=1S/C9H7N5/c10-8-7-9(14-13-8)12-6-4-2-1-3-5(6)11-7/h1-4H,(H3,10,12,13,14) |
| InChIKey | DWHVZCLBMTZRQM-UHFFFAOYSA-N |
| SMILES | C1=CC2=NC3=C(NN=C3N=C2C=C1)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
