Famotidine

  • CAT Number: A001057
  • CAS Number: 76824-35-6
  • Molecular Formula: C8H15N7O2S3
  • Molecular Weight: 337.45
  • Purity: ≥95%
Inquiry Now

Famotidine (Cat No.: A001057) is a histamine H2 receptor antagonist with strong selectivity and can permanently inhibit gastric acid secretion. It is applicable to gastric and duodenal ulcer, reflux esophagitis, upper gastrointestinal bleeding, etc.

Catalog Number A001057
CAS Number 76824-35-6
Molecular Formula

C8H15N7O2S3

Purity 95%
Target Histamine Receptor
Solubility Soluble in DMSO > 10 mM
Storage -20°C
InChI 1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
InChIKey XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N
Reference

1: Kushwaha A, Singh MP. A New Approach To Enhance The Solubility Of Famotidine
Tablet By Using Naturally Isolated Pear Starch. Recent Pat Drug Deliv Formul.
2018 Jan 4. doi: 10.2174/1872211312666180105113037. [Epub ahead of print] PubMed
PMID: 29303081.
<br>

2: Kiszkiel-Taudul I, Starczewska B, Karpińska J, Kasabu&#322;a M. Application of
Micellar Extraction for Isolation of Famotidine from Aqueous Samples Prior to its
Chromatographic Determination. J Surfactants Deterg. 2017;20(6):1401-1409. doi:
10.1007/s11743-017-2003-3. Epub 2017 Aug 12. PubMed PMID: 29200812; PubMed
Central PMCID: PMC5686284.

<br>
3: Saheera S, Potnuri AG, Nair R. Histamine-2 receptor antagonist famotidine
modulates cardiac stem cell characteristics in hypertensive heart disease. PeerJ.
2017 Oct 9;5:e3882. doi: 10.7717/peerj.3882. eCollection 2017. PubMed PMID:
29038754; PubMed Central PMCID: PMC5637875.
<br>

4: Elzanfaly ES, Zaazaa HE, Soudi AT, Salem MY. Multivariate Validated Models for
Simultaneous Determination of Ibuprofen and Famotidine in the Presence of Related
Substances. J AOAC Int. 2017 Sep 6. doi: 10.5740/jaoacint.17-0053. [Epub ahead of
print] PubMed PMID: 28874228.

<br>
5: Narumi K, Sato Y, Kobayashi M, Furugen A, Kasashi K, Yamada T, Teshima T,
Iseki K. Effects of proton pump inhibitors and famotidine on elimination of
plasma methotrexate: Evaluation of drug-drug interactions mediated by organic
anion transporter 3. Biopharm Drug Dispos. 2017 Dec;38(9):501-508. doi:
10.1002/bdd.2091. Epub 2017 Nov 6. PubMed PMID: 28801980.
<br>

6: Feng HP, Vaddady P, Guo Z, Liu F, Panebianco D, Levine V, Caro L, Butterton
JR, Iwamoto M, Yeh WW. No Pharmacokinetic Interaction Between the Hepatitis C
Virus Inhibitors Elbasvir/Grazoprevir and Famotidine or Pantoprazole. Clin Transl
Sci. 2017 Sep;10(5):360-365. doi: 10.1111/cts.12465. Epub 2017 Jun 17. PubMed
PMID: 28625018; PubMed Central PMCID: PMC5593162.

<br>
7: Hojo M, Nagahara A, Asaoka D, Takeda T, Izumi K, Matsumoto K, Ueyama H,
Shimada Y, Matsumoto K, Nojiri S, Watanabe S. A Randomized, Double-Blind, Pilot
Study of the Effect of Famotidine on Acotiamide Treatment for Functional
Dyspepsia. Digestion. 2017;96(1):5-12. doi: 10.1159/000477345. Epub 2017 Jun 13.
PubMed PMID: 28605740; PubMed Central PMCID: PMC5637310.
<br>

8: Naeeji A, Mozdarani H, Shabestani Monfared A, Faeghi F, Ahmadi AA, Gholami M,
Behzadi R, Momtaz MR. Oral Administration of Vitamin C, Cimetidine and Famotidine
on Micronuclei Induced by Low Dose Radiation in Mouse Bone Marrow Cells. J Biomed
Phys Eng. 2017 Jun 1;7(2):117-126. eCollection 2017 Jun. PubMed PMID: 28580333;
PubMed Central PMCID: PMC5447248.
<br>

9: Verma U, Naik JB, Patil JS, Yadava SK. Screening of process variables to
enhance the solubility of famotidine with 2-HydroxyPropyl-β-Cyclodextrin & PVP
K-30 by using Plackett-Burman design approach. Mater Sci Eng C Mater Biol Appl.
2017 Aug 1;77:282-292. doi: 10.1016/j.msec.2017.03.238. Epub 2017 Mar 28. PubMed
PMID: 28532031.
<br>

10: Khalifa AM, Abdul Rasool BK. Optimized Mucoadhesive Coated Niosomes as a
Sustained Oral Delivery System of Famotidine. AAPS PharmSciTech. 2017
Nov;18(8):3064-3075. doi: 10.1208/s12249-017-0780-7. Epub 2017 May 17. PubMed
PMID: 28516414.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!