NSC319726

  • CAT Number: I004668
  • CAS Number: 71555-25-4
  • Molecular Formula: C11H14N4S
  • Molecular Weight: 234.32
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NSC 319726 (Cat No.:I004668) is an activator of p53(R175) mutant, inhibits the growth of cells expressing mutant p53, acts on p53(R175) mutant, IC50 is 8 nM, has no effect on p53 wild-type cells inhibition.

Catalog Number I004668
CAS Number 71555-25-4
Molecular Formula

C11H14N4S

Purity 95%
Target p53
Solubility DMSO: ≤ 27.5 mg/mL
Storage Store at -20°C
IC50 8 nM
IUPAC Name N-[(E)-1-pyridin-2-ylethylideneamino]azetidine-1-carbothioamide
InChI InChI=1S/C11H14N4S/c1-9(10-5-2-3-6-12-10)13-14-11(16)15-7-4-8-15/h2-3,5-6H,4,7-8H2,1H3,(H,14,16)/b13-9+
InChIKey XDHBUMNIQRLHGO-UKTHLTGXSA-N
SMILES CC(=NNC(=S)N1CCC1)C2=CC=CC=N2

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