NSC228155

  • CAT Number: I011590
  • CAS Number: 113104-25-9
  • Molecular Formula: C11H6N4O4S
  • Molecular Weight: 290.253
  • Purity: ≥95%
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NSC228155(CAT: I011590)is a small molecule inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which is involved in cholesterol biosynthesis. By inhibiting HMG-CoA reductase, NSC228155 reduces the production of cholesterol in the liver, leading to decreased levels of low-density lipoprotein (LDL) or “bad” cholesterol in the bloodstream. This property has led to its use in research and the development of pharmaceuticals for the treatment of hypercholesterolemia and other cardiovascular diseases. NSC228155 has also been investigated for its potential anticancer effects, as it may inhibit the growth and proliferation of cancer cells.

Catalog Number I011590
CAS Number 113104-25-9
Molecular Formula

C11H6N4O4S

Purity 95%
Target EGFR
Solubility Soluble in DMSO
Storage Store at -20°C
IUPAC Name 7-nitro-4-(1-oxidopyridin-1-ium-2-yl)sulfanyl-2,1,3-benzoxadiazole
InChI InChI=1S/C11H6N4O4S/c16-14-6-2-1-3-9(14)20-8-5-4-7(15(17)18)10-11(8)13-19-12-10/h1-6H
InChIKey ICCFXXDUYSPKOL-UHFFFAOYSA-N
SMILES C1=CC=[N+](C(=C1)SC2=CC=C(C3=NON=C23)[N+](=O)[O-])[O-]

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