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NSC-207895

NSC-207895

  • CAT Number: I002367
  • CAS Number: 58131-57-0
  • Molecular Formula: C11H13N5O4
  • Molecular Weight: 279.25
  • Purity: ≥95%
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NSC-207895（Cat No.:I002367） has been shown to inhibit the MDMX protein with an IC50 of 2.5 μM. This inhibition promotes p53 stabilization/activation and DNA damage while also regulating the MDM2 E3 ligase. NSC-207895’s ability to modulate these key proteins involved in cancer cell survival and proliferation suggests its potential as an anti-cancer agent. However, further studies are required to determine its effectiveness and safety for clinical use.

Catalog Number I002367
CAS Number 58131-57-0
Molecular Formula

C11H13N5O4

Purity 95%
Target MDM2
Solubility Limited solubility
Storage Store at -20°C
IUPAC Name 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium
InChI InChI=1S/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3
InChIKey MWFZDJLPWDCQIL-UHFFFAOYSA-N
SMILES CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]

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