For research use only. Not for therapeutic Use.
Norverapamil-d7 hydrochloride（Cat No.:R044076）is a deuterated form of norverapamil, the major active metabolite of the calcium channel blocker verapamil. In this analog, seven hydrogen atoms are replaced with deuterium to enhance metabolic stability and allow precise quantification in mass spectrometry-based assays. The hydrochloride salt improves solubility for analytical and pharmacokinetic studies. Norverapamil-d7 is primarily used as an internal standard in bioanalytical methods for monitoring verapamil and its metabolites in biological samples. It supports drug metabolism, pharmacokinetic profiling, and therapeutic drug monitoring in cardiovascular and clinical pharmacology research.
| CAS Number | 1216413-74-9 |
| Synonyms | 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)pentanenitrile;hydrochloride |
| Molecular Formula | C26H30D7ClN2O4 |
| Purity | ≥95% |
| IUPAC Name | 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)pentanenitrile;hydrochloride |
| InChI | InChI=1S/C26H36N2O4.ClH/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5;/h8-11,16-17,19,28H,7,12-15H2,1-6H3;1H/i1D3,2D3,19D; |
| InChIKey | OEAFTRIDBHSJDC-GUZHUBCOSA-N |
| SMILES | [2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
