Norgestimate metabolite norelgestromin-d6

• CAT Number: R007958
• CAS Number: 1263184-13-9
• Molecular Formula: C21H23D6NO2
• Molecular Weight: 333.50
• Purity: ≥95%
• Synonyms: (3E,8R,9S,10R,13S,14S,17R)-2,2,4,6,6,10-hexadeuterio-13-ethyl-17-ethynyl-3-hydroxyimino-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-ol
• IUPAC Name: (3Z,8R,9S,10R,13S,14S,17R)-2,2,4,6,6,10-hexadeuterio-13-ethyl-17-ethynyl-3-hydroxyimino-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-ol
• InChI: InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15-/t16-,17+,18+,19-,20-,21-/m0/s1/i5D2,6D2,13D,16D
• InChIKey: ISHXLNHNDMZNMC-VWACAVPESA-N
• SMILES: [2H]C\1=C2[C@](CC(/C1=N/O)([2H])[2H])([C@H]3CC[C@]4([C@H]([C@@H]3CC2([2H])[2H])CC[C@]4(C#C)O)CC)[2H]

Norgestimate metabolite norelgestromin-d6（Cat No.:R007958）is a deuterated form of norelgestromin, a progestin commonly used in hormonal contraceptives. The “d6” designation indicates the incorporation of six deuterium atoms, a stable isotope of hydrogen, replacing the hydrogen atoms in the molecule. This modification is used in pharmacokinetic studies to trace the metabolism and bioavailability of the drug in the body. Norelgestromin-d6 is primarily employed in research to investigate the pharmacodynamics, metabolism, and clearance of progestin-based contraceptives, aiding in the development of more efficient and tailored contraceptive therapies.