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Nigericin sodium salt

Nigericin sodium salt

  • CAT Number: I002977
  • CAS Number: 28643-80-3
  • Molecular Formula: C40H67O11 • Na
  • Molecular Weight: 747
  • Purity: ≥95%
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<p style=/line-height:25px/>Nigericin (sodium salt) is potassium ionophore, exchanges K+ for H+ across biological membranes. Also acts as an ionophore for Pb2+ with no activity with other divalent cations.<br>Nigericin (sodium salt) induced egress depends on an efflux of potassium from the cell and requires phospholipase C function and parasite motility.</p>

Catalog Number I002977
CAS Number 28643-80-3
Molecular Formula

C40H67O11 • Na

Purity 95%
Solubility 10 mM in ethanol, DMSO: ＜ 0.3 mg/mL, H2O: ＜ 0.3 mg/mL
Storage -20°C
InChIKey MOYOTUKECQMGHE-HOIKPYQJSA-M
Reference

<p style=/line-height:25px/>
<br>[1]. Hamidinia SA et al. The ionophore nigericin transports Pb2+ with high activity and selectivity: a comparison to monensin and ionomycin. Biochemistry. 2004 Dec 21;43(50):15956-65.
<br>[2]. Eytan GD et al. Energy-linked transhydrogenase. Effects of valinomycin and nigericin on the ATP-driven transhydrogenasereaction catalyzed by reconstituted transhydrogenase-ATPase vesicles. J Biol Chem, 1990 Aug 5, 265(22):12949-54.
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