NHC-diphosphate triammonium

• CAT Number: I044508
• Molecular Formula: C9H24N6O12P2
• Molecular Weight: 470.27
• Purity: ≥95%
• Synonyms: azane;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl phosphono hydrogen phosphate
• InChI: InChI=1S/C9H15N3O12P2.3H3N/c13-6-4(3-22-26(20,21)24-25(17,18)19)23-8(7(6)14)12-2-1-5(11-16)10-9(12)15;;;/h1-2,4,6-8,13-14,16H,3H2,(H,20,21)(H,10,11,15)(H2,17,18,19);3*1H3/t4-,6-,7-,8-;;;/m1.../s1
• InChIKey: IFDLJBUQQGSKTM-LLWADOMFSA-N
• SMILES: C1=CN(C(=O)N=C1NO)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O.N.N.N

NHC-diphosphate triammonium（Cat No.:I044508）is a water-soluble salt form of the diphosphate derivative of N-hydroxycytidine (NHC), the active metabolite of the antiviral drug molnupiravir. It mimics natural nucleotides and is incorporated into viral RNA by RNA-dependent RNA polymerases, inducing lethal mutagenesis in viruses such as SARS-CoV-2. The triammonium salt enhances solubility and stability, making it suitable for biochemical assays and antiviral mechanism studies. NHC-diphosphate is a key pharmacologically active intermediate responsible for the broad-spectrum antiviral activity of molnupiravir, widely used in research on viral replication and RNA virus inhibition.