Netarsudil - CAS 1254032-66-0
Netarsudil (CAT: I007702) is a medication used in the treatment of glaucoma and ocular hypertension. It is a Rho kinase (ROCK) inhibitor that works by reducing intraocular pressure (IOP) through several mechanisms. Netarsudil inhibits ROCK, resulting in the relaxation of the trabecular meshwork, which improves the outflow of aqueous humor from the eye. Additionally, it decreases episcleral venous pressure, further aiding in the reduction of IOP. Netarsudil is typically administered as eye drops and has been found to effectively lower IOP, making it a valuable therapeutic option for individuals with glaucoma or ocular hypertension.
* For research use only. Not for human or veterinary use.
|Synonyms||AR-11324; AR 11324; AR11324; Netarsudil;(S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate|
|Target:||Rho-associated protein kinase inhibitor|
|Solubility||Soluble in DMSO, not in water|
|Storage||0 - 4°C for short term , or -20°C for long term.|
|IUPAC Name||[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate|