Navitoclax-piperazine

  • CAT Number: I017193
  • CAS Number: 2143096-93-7
  • Molecular Formula: C₄₇H₅₆ClF₃N₆O₅S₃
  • Molecular Weight: 973.63
  • Purity: ≥95%
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Navitoclax-piperazine (Cat.No:I017193) is a potent and selective inhibitor of B-cell lymphoma 2 (Bcl-2) proteins. It is used in the treatment of various types of cancer, including chronic lymphocytic leukemia and small cell lung cancer. Navitoclax-piperazine works by blocking the anti-apoptotic proteins in cancer cells, leading to cell death. It is being investigated as a promising therapeutic option in oncology.

Catalog Number I017193
CAS Number 2143096-93-7
Molecular Formula

C₄₇H₅₆ClF₃N₆O₅S₃

Purity 95%
Reference

[1]. Sajid Khan, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med 25, 1938–1947 (2019).

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