NAPHTHOL AS-BI PHOSPHATE

• CAT Number: M123293
• CAS Number: 1919-91-1
• Molecular Formula: C18H15BrNO6P
• Molecular Weight: 452.197
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: [6-bromo-3-[(2-methoxyphenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate
• InChI: InChI=1S/C18H15BrNO6P/c1-25-16-5-3-2-4-15(16)20-18(21)14-9-12-8-13(19)7-6-11(12)10-17(14)26-27(22,23)24/h2-10H,1H3,(H,20,21)(H2,22,23,24)
• InChIKey: HUXIAXQSTATULQ-UHFFFAOYSA-N
• SMILES: COC1=CC=CC=C1NC(=O)C2=C(C=C3C=CC(=CC3=C2)Br)OP(=O)(O)O

Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-BI-phosphate is converted to naphthol AS-BI (N-ASBI) which displays excitation/emission spectra of 405/515 nm, respectively. N-ASBI fluorescence is a quantitative marker of acid and alkaline phosphatase activity. The concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. Thus, acid and alkaline phosphatases are often used as clinical markers of disease.