NAP 226-90

• CAT Number: R005408
• CAS Number: 139306-10-8
• Molecular Formula: C10H15NO
• Molecular Weight: 165.24
• Purity: ≥95%
• Synonyms: (S)-3-[1-(Dimethylamino)ethyl]phenol; 3-[(1S)-1-(Dimethylamino)ethyl]phenol
• Storage: -20°C
• IUPAC Name: 3-[(1S)-1-(dimethylamino)ethyl]phenol
• InChI: InChI=1S/C10H15NO/c1-8(11(2)3)9-5-4-6-10(12)7-9/h4-8,12H,1-3H3/t8-/m0/s1
• InChIKey: GQZXRLWUYONVCP-QMMMGPOBSA-N
• SMILES: CC(C1=CC(=CC=C1)O)N(C)C

NAP 226-90 (Cat No.: R005408) is a synthetic compound known for its neuroprotective and cognitive-enhancing properties, particularly within Alzheimer’s disease research. It belongs to the class of activity-dependent neuroprotective proteins (ADNP)-derived peptides. NAP 226-90, also referred to as davunetide, stabilizes microtubules and supports neuronal integrity by interacting with tubulin. It has demonstrated potential in protecting against tau pathology and oxidative stress in preclinical models. Due to its small peptide structure, NAP 226-90 is capable of crossing the blood-brain barrier, making it a promising therapeutic candidate.