N-Mal-N-bis(PEG2-NH-Boc)

• CAT Number: I015891
• CAS Number: 2128735-26-0
• Molecular Formula: C29H50N4O11
• Molecular Weight: 630.73
• Purity: ≥95%
• Synonyms: tert-butyl N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoyl-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethyl]carbamate
• InChI: InChI=1S/C29H50N4O11/c1-28(2,3)43-26(37)30-10-15-39-19-21-41-17-13-32(23(34)9-12-33-24(35)7-8-25(33)36)14-18-42-22-20-40-16-11-31-27(38)44-29(4,5)6/h7-8H,9-22H2,1-6H3,(H,30,37)(H,31,38)
• InChIKey: YVJUWISEQMFTOR-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCN(CCOCCOCCNC(=O)OC(C)(C)C)C(=O)CCN1C(=O)C=CC1=O

N-Mal-N-bis(PEG2-NH-Boc)（Cat No.:I015891）is a heterobifunctional PEG derivative containing a maleimide group and two Boc-protected amines, each linked via PEG₂ spacers. The maleimide moiety reacts selectively with thiol groups to form stable thioether linkages under mild conditions, enabling efficient site-specific conjugation. The Boc-protected amines can be deprotected to expose primary amines for further coupling with carboxyls, NHS esters, or aldehydes. The PEG₂ chains provide hydrophilicity, flexibility, and reduced steric hindrance. This reagent is widely applied in bioconjugation, nanoparticle modification, polymer engineering, and targeted drug delivery research.