N-Hexadecanoyl-ceramide trihexoside

• CAT Number: R067974
• Molecular Formula: C52H97NO18
• Molecular Weight: 1024
• Purity: ≥95%
• Synonyms: N-C16:0-Ceramide trihexoside; N-Hexadecanoyl globotriaosylceramide
• Solubility: DMSO, hot methanol, chloroform/methanol, 2:1
• Storage: Store at -20°C

Reference

1. M. Fuller et al. “Urinary Lipid Profiling for the Identification of Fabry Hemizygotes and Heterozygotes” Clinical Chemistry, Vol. 51 pp. 688-694, 20052. S. Ashkenazi and T. G. Cleary, “Rapid method to detect shiga toxin and shiga-like toxin I based on binding to globotriosyl ceramide (Gb3), their naturalreceptor.” J Clin Microbio. June; 27(6): 1145-1150, 19893. S. Bekri, O. Lidove, R. Jaussaud, B. Knebelmann, F. Barbey. /The role of ceramide trihexoside (globotriaosylceramide) in the diagnosis and follow-up ofthe efficacy of treatment of Fabry disease: a review of the literature/. Cardiovasc Hematol Agents Med Chem 4 (4): 289–97, October 20064. J. E. Groener, B. J. Poorthuis, S. Kuiper, M. T. Helmond, C. E. Hollak, J. M. Aerts. “HPLC for simultaneous quantification of total ceramide,glucosylceramide, and ceramide trihexoside concentrations in plasma.” Clin Chem., Apr;53(4):742-7, 2007. Epub Mar 1 20075. C. Menge, I. Stamm, M. Wuhrer, R. Geyer, L. H. Wieler, G. Baljer. “Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed bybovine lymphocytes upon activation in vitro.” Vet Immunol Immunopathol., Nov;83(1-2):19-36, 2001