N-Acetylcysteine Amide

• CAT Number: R036117
• CAS Number: 38520-57-9
• Molecular Formula: C5H10N2O2S
• Molecular Weight: 162.21
• Purity: ≥95%
• Synonyms: (2R)-2-(Acetylamino)-3-mercaptopropanamide;?N-Acetyl-L-cysteinamide
• Target: NF-κB
• Storage: Store at -20C
• IUPAC Name: (2R)-2-acetamido-3-sulfanylpropanamide
• InChI: InChI=1S/C5H10N2O2S/c1-3(8)7-4(2-10)5(6)9/h4,10H,2H2,1H3,(H2,6,9)(H,7,8)/t4-/m0/s1
• InChIKey: UJCHIZDEQZMODR-BYPYZUCNSA-N
• SMILES: CC(=O)N[C@@H](CS)C(=O)N

N-Acetylcysteine Amide (Cat No.:R036117) is a modified derivative of N-acetylcysteine (NAC), in which the carboxyl group is replaced with an amide, enhancing its lipophilicity and cellular uptake. NACA retains the antioxidant and mucolytic properties of NAC but offers improved bioavailability and stability. It effectively replenishes intracellular glutathione levels and protects against oxidative stress and free radical damage. NACA is studied for its therapeutic potential in neurodegenerative diseases, cardiovascular disorders, and as a cytoprotective agent. Its enhanced pharmacokinetic profile makes it a promising candidate for clinical and biomedical research applications.