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Home > Reference Standards>Phosphodiesterase (PDE)> > N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride

  • CAT Number: R000011
  • CAS Number: 61714-27-0
  • Molecular Formula: C16H22Cl2N2O2S
  • Molecular Weight: 377.33
  • Purity: ≥95%
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W-7hydrochloride（Cat No.:R000011） is a selective calmodulin antagonist with inhibitory effects on Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase (IC50 values of 28μM and 51μM, respectively). It possesses apoptotic-inducing properties and exhibits anticancer activity. As a calmodulin inhibitor, W-7hydrochloride interferes with cellular signaling pathways involved in cell growth and survival, making it a potential candidate for cancer therapy.

Catalog Number R000011
CAS Number 61714-27-0
Synonyms

W7

Molecular Formula

C16H22Cl2N2O2S

Purity 95%
Target Calcium Channel
Solubility Soluble in DMSO > 10 mM
Storage Store at -20°C
IUPAC Name N-(6-aminohexyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride
InChI InChI=1S/C16H21ClN2O2S.ClH/c17-15-9-5-8-14-13(15)7-6-10-16(14)22(20,21)19-12-4-2-1-3-11-18;/h5-10,19H,1-4,11-12,18H2;1H
InChIKey OMMOSRLIFSCDBL-UHFFFAOYSA-N
SMILES C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCCCCCN.Cl

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