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MX69

MX69

  • CAT Number: I000088
  • CAS Number: 1005264-47-0
  • Molecular Formula: C₂₇H₂₆N₂O₄S
  • Molecular Weight: 474.58
  • Purity: ≥95%
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MX69 (Cat No.:I000088) is an MDM2/XIAP inhibitor commonly used in anticancer research. MX69-induced MDM2 downregulation results not only in the inhibition of XIAP expression but also in the activation of p53, which contributes to cancer cell apoptosis in vitro. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I000088
CAS Number 1005264-47-0
Molecular Formula

C₂₇H₂₆N₂O₄S

Purity 95%
Solubility DMSO: ≥ 30 mg/mL
Storage Store at -20C
IUPAC Name 4-[8-[(3,4-dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid
InChI InChI=1S/C27H26N2O4S/c1-16-6-11-20(14-17(16)2)29-34(32,33)21-12-13-25-24(15-21)22-4-3-5-23(22)26(28-25)18-7-9-19(10-8-18)27(30)31/h3-4,6-15,22-23,26,28-29H,5H2,1-2H3,(H,30,31)
InChIKey XCBONKHCCRJMNW-UHFFFAOYSA-N
SMILES CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC3=C(C=C2)NC(C4C3C=CC4)C5=CC=C(C=C5)C(=O)O)C
Reference

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<br>[1]. Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636.

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