Mulberroside A

• CAT Number: I000177
• CAS Number: 102841-42-9
• Molecular Formula: C26H32O14
• Molecular Weight: 568.52
• Purity: 98%
• Solubility: DMSO: 40 mg/mL
• Storage: Store at -20°C
• IC50: 1.29 μmol/L (inhibition of the monophenolase activity); KI value: 0.385 μmol/L (the inhibition constant of the effectors on tyrosinase); KIS value: 0.177 μmol/L (the inhibition constant of the enzyme-substrate complex) [3]
• IUPAC Name: (2S,3R,4S,5S,6R)-2-[3-hydroxy-4-[(E)-2-[3-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C26H32O14/c27-9-17-19(31)21(33)23(35)25(39-17)37-14-4-3-12(16(30)8-14)2-1-11-5-13(29)7-15(6-11)38-26-24(36)22(34)20(32)18(10-28)40-26/h1-8,17-36H,9-10H2/b2-1+/t17-,18-,19-,20-,21+,22+,23-,24-,25-,26-/m1/s1
• InChIKey: HPSWAEGGWLOOKT-VUNDNAJOSA-N
• SMILES: C1=CC(=C(C=C1OC2C(C(C(C(O2)CO)O)O)O)O)C=CC3=CC(=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O)O

Mulberroside A (Cat.No:I000177) is a natural compound isolated from the root bark of the mulberry tree (Morus alba). It belongs to the class of flavonoid glycosides and exhibits various biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Mulberroside A has shown potential in preclinical studies for its ability to inhibit tumor growth and protect against oxidative stress. Further research is underway to explore its therapeutic applications.

Reference

[1]. Cai-Ping Wang, et al. Mulberroside a protects against ischemic impairment in primary culture of rat cortical neurons after oxygen–glucose deprivation followed by reperfusion. Journal of Neuroscience Research Volume 92, Issue 7, pages 944–954, July 2014
[2]. Yuhua Li, et al. Down-regulation of P-gp expression and function after Mulberroside A treatment: Potential role of protein kinase C and NF-kappa B. Chemico-Biological Interactions Volume 213, 25 April 2014, Pages 44–50
[3]. Shu Wang, et al. An efficient preparation of mulberroside a from the branch bark of mulberry and its effect on the inhibition of tyrosinase activity. PloS one 2014, 9 (10): e109396