MOG peptide (35-55)

• CAT Number: I042535
• CAS Number: 2022956-48-3
• Molecular Formula: C118H178N36O28S
• Molecular Weight: 2580.97
• Purity: ≥95%
• IUPAC Name: (4S)-5-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-1,4-dioxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C118H178N36O28S/c1-61(2)47-80(104(171)144-81(49-66-30-34-70(157)35-31-66)105(172)140-76(26-17-42-130-116(123)124)100(167)146-86(53-90(121)159)99(166)134-56-91(160)137-75(97(122)164)25-15-16-41-119)143-109(176)85(52-69-55-129-60-136-69)148-113(180)95(63(5)6)153-114(181)96(64(7)8)152-102(169)78(28-19-44-132-118(127)128)142-110(177)87(58-155)149-107(174)83(48-65-21-11-10-12-22-65)147-111(178)89-29-20-45-154(89)115(182)88(59-156)150-101(168)77(27-18-43-131-117(125)126)141-106(173)82(50-67-32-36-71(158)37-33-67)145-108(175)84(51-68-54-133-74-24-14-13-23-72(68)74)138-92(161)57-135-112(179)94(62(3)4)151-103(170)79(38-39-93(162)163)139-98(165)73(120)40-46-183-9/h10-14,21-24,30-37,54-55,60-64,73,75-89,94-96,133,155-158H,15-20,25-29,38-53,56-59,119-120H2,1-9H3,(H2,121,159)(H2,122,164)(H,129,136)(H,134,166)(H,135,179)(H,137,160)(H,138,161)(H,139,165)(H,140,172)(H,141,173)(H,142,177)(H,143,176)(H,144,171)(H,145,175)(H,146,167)(H,147,178)(H,148,180)(H,149,174)(H,150,168)(H,151,170)(H,152,169)(H,153,181)(H,162,163)(H4,123,124,130)(H4,125,126,131)(H4,127,128,132)/t73-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,94-,95-,96-/m0/s1
• InChIKey: FVIBVVRKMMTFIW-DDJPMISGSA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](CC6=CNC7=CC=CC=C76)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)N

MOG peptide (35-55)（Cat No.:I042535）is a synthetic fragment of the myelin oligodendrocyte glycoprotein (MOG), a protein expressed in the central nervous system. This specific peptide sequence is often used in experimental models to study autoimmune diseases, particularly multiple sclerosis (MS). MOG peptide (35-55) induces an immune response that mimics MS, as it triggers the activation of T cells, leading to inflammation and demyelination in animal models. This makes it a valuable tool for understanding the pathogenesis of MS and for developing potential therapies targeting autoimmune and neuroinflammatory conditions.