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Bax channel blocker

Bax channel blocker

  • CAT Number: I011471
  • CAS Number: 335165-68-9
  • Molecular Formula: C19H23Br2Cl2N3O
  • Molecular Weight: 540.121
  • Purity: ≥95%
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The Bax channel blocker (CAT: I011471) is a small molecule inhibitor that targets the Bax protein, which plays a critical role in regulating programmed cell death (apoptosis). Bax is a pro-apoptotic protein that promotes the release of cytochrome c from mitochondria, leading to cell death. The Bax channel blocker works by binding to the Bax protein and inhibiting its ability to form channels in the mitochondrial membrane, thereby preventing cytochrome c release and reducing cell death. This compound has potential therapeutic applications in the treatment of diseases associated with abnormal cell death, such as cancer and neurodegenerative disorders. However, further research is needed to fully understand the pharmacological effects and potential clinical applications of the Bax channel blocker.

Catalog Number I011471
CAS Number 335165-68-9
Synonyms

1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol;dihydrochloride

Molecular Formula

C19H23Br2Cl2N3O

Purity 95%
Target Bcl-2 Family
Solubility Soluble in DMSO > 10 mM
Storage Desiccate at RT
IUPAC Name 1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol;dihydrochloride
InChI InChI=1S/C19H21Br2N3O.2ClH/c20-13-1-3-18-16(9-13)17-10-14(21)2-4-19(17)24(18)12-15(25)11-23-7-5-22-6-8-23;;/h1-4,9-10,15,22,25H,5-8,11-12H2;2*1H
InChIKey HWFKCAFKXZFOQT-UHFFFAOYSA-N
SMILES C1CN(CCN1)CC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)O.Cl.Cl

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