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MLN2480

MLN2480

  • CAT Number: I000407
  • CAS Number: 1096708-71-2
  • Molecular Formula: C₁₇H₁₂Cl₂F₃N₇O₂S
  • Molecular Weight: 506.29
  • Purity: ≥95%
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MLN2480 (Cat No.:I000407)also known as BIIB-024, TAK580, AMG-2112819, BSK1369, or DAY-101, is an orally administered inhibitor of Raf kinases. By targeting Raf kinases, MLN2480 interferes with the signaling pathways involved in cell growth and proliferation. As a result, it has the potential to inhibit the growth of cancer cells that rely on aberrant Raf kinase activity. MLN2480 is being investigated for its therapeutic potential in various types of cancer, and its oral formulation offers convenience and ease of administration for patients undergoing treatment.

Catalog Number I000407
CAS Number 1096708-71-2
Molecular Formula

C₁₇H₁₂Cl₂F₃N₇O₂S

Purity 95%
Target Raf
Solubility 10 mM in DMSO
Storage 3 years -20C powder
InChI InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1
InChIKey VWMJHAFYPMOMGF-ZCFIWIBFSA-N
SMILES CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
Reference

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<br>[1]. Macauley, D, et al. Drugs Fut 2012, 37(6): 451
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