For research use only. Not for therapeutic Use.
MK-1903（Cat No.:I008050）is a selective agonist of GPR119, a G protein-coupled receptor primarily expressed in pancreatic β-cells and intestinal L-cells. Activation of GPR119 by MK-1903 enhances glucose-dependent insulin secretion and stimulates the release of incretin hormones such as GLP-1, supporting improved glycemic control. It has been investigated for its potential in treating type 2 diabetes and metabolic disorders. MK-1903 is used in preclinical and clinical research to study GPR119-mediated signaling pathways, β-cell function, and incretin-based mechanisms. It serves as a valuable tool for developing novel glucose-lowering therapies.
| CAS Number | 1268882-43-4 |
| Synonyms | (2R,4R)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid |
| Molecular Formula | C8H8N2O2 |
| Purity | ≥95% |
| IUPAC Name | (2R,4R)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid |
| InChI | InChI=1S/C8H8N2O2/c11-8(12)7-5-2-3-1-4(3)6(5)9-10-7/h3-4H,1-2H2,(H,9,10)(H,11,12)/t3-,4-/m1/s1 |
| InChIKey | CUTZNERBKDMLAP-QWWZWVQMSA-N |
| SMILES | C1[C@H]2[C@@H]1C3=C(C2)C(=NN3)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
