For research use only. Not for therapeutic Use.
Mivacurium dichloride（Cat No.:R008458）is a short-acting, non-depolarizing neuromuscular blocking agent belonging to the benzylisoquinolinium class. It acts as a competitive antagonist at nicotinic acetylcholine receptors in the neuromuscular junction, preventing depolarization and inducing skeletal muscle relaxation. Clinically, it has been used as an adjunct to anesthesia to facilitate tracheal intubation and provide muscle relaxation during surgical procedures. Its rapid onset and short duration are due to hydrolysis by plasma cholinesterases. In research, mivacurium dichloride is studied in pharmacology, anesthesiology, and neuromuscular transmission models.
| CAS Number | 106861-44-3 |
| Synonyms | bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;dichloride |
| Molecular Formula | C58H80Cl2N2O14 |
| Purity | ≥95% |
| IUPAC Name | bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;dichloride |
| InChI | InChI=1S/C58H80N2O14.2ClH/c1-59(25-21-41-35-47(63-3)49(65-5)37-43(41)45(59)29-39-31-51(67-7)57(71-11)52(32-39)68-8)23-17-27-73-55(61)19-15-13-14-16-20-56(62)74-28-18-24-60(2)26-22-42-36-48(64-4)50(66-6)38-44(42)46(60)30-40-33-53(69-9)58(72-12)54(34-40)70-10;;/h13-14,31-38,45-46H,15-30H2,1-12H3;2*1H/q+2;;/p-2/b14-13+;;/t45-,46-,59?,60?;;/m1../s1 |
| InChIKey | WMSYWJSZGVOIJW-ONUALHDOSA-L |
| SMILES | C[N+]1(CCC2=CC(=C(C=C2[C@H]1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CC/C=C/CCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5[C@H]4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
