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Mitoxantrone HCl

Mitoxantrone HCl

  • CAT Number: A000577
  • CAS Number: 70476-82-3
  • Molecular Formula: C22H28N4O6 • 2HCl
  • Molecular Weight: 517.4
  • Purity: ≥95%
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<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Mitoxantrone HCl (CAS 70476-82-3) is the hydrochloride salt of&nbsp;Mitoxantrone. Mitoxantrone is a sparingly soluble (0.734 mg/mL) anti-cancer agent.<br />
Mitoxantrone inhibits division of T-cells, B-cells, and macrophages by preventing DNA repair and synthesis, however, this also occurs in healthy cells.</span></span></span></p>

Catalog Number A000577
CAS Number 70476-82-3
Molecular Formula

C22H28N4O6 • 2HCl

Purity 95%
Target Topoisomerase II
Storage 3 years -20C powder
IUPAC Name 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
InChI InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChIKey ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl
Reference

<p>
1.Fox, E. J. /Mechanism of Action of Mitoxantrone./<em> PubMed</em> 63.12 (2004): n. pag.<em>www.ncbi.gov</em>. MS Clinic of Central Texas, 28 Dec. 2004. Web. 30 Aug. 2012.</p>
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