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Misoprostol Acid (10 mg in 1 mL Methyl Acetate)

Misoprostol Acid (10 mg in 1 mL Methyl Acetate)

  • CAT Number: R008464
  • CAS Number: 112137-89-0
  • Molecular Formula: C21H36O5
  • Molecular Weight: 368.5
  • Purity: ≥95%
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Misoprostol is a prostaglandin E<sub>1</sub> (Item No. <span class=/itemid/>13010</span>) analog with agonist activity mediated by EP<sub>2</sub>, EP<sub>3</sub>, and EP<sub>4</sub> receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED<sub>50</sub> = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC<sub>50</sub> = 0.35 µM), and relax fetal rabbit ductus arteriosus (EC<sub>50</sub> = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-<wbr></wbr>486; Item No. <span class=/itemid/>10006317</span>) for the oral induction of first trimester abortion. Misoprostol contains a C-<wbr></wbr>1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

Catalog Number R008464
CAS Number 112137-89-0
Molecular Formula

C21H36O5

Purity 95%
Storage -20°C
InChIKey CNWGPXZGIIOYDL-MKYGPDKMSA-N

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