Mirodenafil dihydrochloride

• CAT Number: I005169
• CAS Number: 862189-96-6
• Molecular Formula: C26H39Cl2N5O5S
• Molecular Weight: 604.59
• Purity: ≥95%
• Target: PDE5
• Solubility: 10 mM in DMSO
• Storage: Store at -20C

Mirodenafil dihydrochloride (Cat.No:I005169) is a selective phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. It works by increasing blood flow to the penis, facilitating and maintaining an erection. Mirodenafil dihydrochloride has shown efficacy and safety in clinical trials and is approved for use in some countries as a treatment for erectile dysfunction.

Reference

[1]. Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction. J Sex Med, 2008. 5(11): p. 2672-80.
[2]. Kim, B.H., et al., Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther, 2009. 31(6): p. 1234-43.
[3]. Shin, K.H., et al., The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study. Clin Ther, 2009. 31(12): p. 3009-20.