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Miconazole Nitrate

Miconazole Nitrate

  • CAT Number: A000397
  • CAS Number: 22832-87-7
  • Molecular Formula: C18H14Cl4N2O • HNO3
  • Molecular Weight: 479.1
  • Purity: ≥95%
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Miconazole nitrate is an imidazole antimycotic compound.&nbsp;Miconazole nitrate targets fungi that cause tinea (ringworm) and athleete/’s foot.</br>Miconazole nitrate increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.

Catalog Number A000397
CAS Number 22832-87-7
Molecular Formula

C18H14Cl4N2O • HNO3

Purity 95%
Storage 3 years -20C powder
InChIKey MCCACAIVAXEFAL-UHFFFAOYSA-N
Reference

<p>Rice L.B. and Ghannoum M.A.. /Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance. Clinical Microbiology Reviews (1999): 501-17.</p><p>Sreedhara, K. H. /Studies on the Mechanism of Action of Miconazole: Effect of Miconazole on Respiration and Cell Permeability of Candida Albicans./ <em>Antimicrobial Agents and Chemotherapy</em> 5.4 (1974): 420-25. <em>w ww.ncbi.gov.</em> American Society for Microbiology. Web. 22 Aug. 2012.</p></span></p>

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