MI-2 is a Menin-MLL interaction inhibitor with IC50 value of 446 ± 28 nM.
Catalog Number | I001086 |
CAS Number | 1271738-62-5 |
Synonyms | 4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine |
Molecular Formula | C₁₈H₂₅N₅S₂ |
Purity | 95% |
Target | Menin-MLL |
Solubility | in DMSO > 10 mM |
Storage | Store at -20°C |
IC50 | 446 ± 28 nM [1] |
InChI | InChI=1S/C18H25N5S2/c1-4-5-13-10-14-15(20-12-21-16(14)24-13)22-6-8-23(9-7-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3 |
InChIKey | SRQYLNYQAPCPIR-UHFFFAOYSA-N |
SMILES | CCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C |
Reference | <p> |