MI-2 - CAS 1271738-62-5

MI-2 is a Menin-MLL interaction inhibitor with IC50 value of 446 ± 28 nM.

Catalog Number: I001086

CAS Number: 1271738-62-5

PubChem Substance ID:355040317

Molecular Formula: C₁₈H₂₅N₅S₂

Molecular Weight:375.55

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine

Property

Molecular Formula: C₁₈H₂₅N₅S₂
Molecular Weight375.55
Target:Menin-MLL
Solubilityin DMSO > 10 mM
Purity≥95%
StorageStore at -20°C
IC50446 ± 28 nM [1]

Computed Descriptor

InChIInChI=1S/C18H25N5S2/c1-4-5-13-10-14-15(20-12-21-16(14)24-13)22-6-8-23(9-7-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3
InChIKeySRQYLNYQAPCPIR-UHFFFAOYSA-N
SMILESCCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C