Sodium salicylate - CAS 54-21-7
Sodium Salicylate(Cat No.: A001025) is the sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells.
Catalog Number: A001025
CAS Number: 54-21-7
Molecular Formula: C7H5NaO3
Molecular Weight:160.10
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | Sodium 2-hydroxybenzoate |
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Property
Molecular Formula: | C7H5NaO3 |
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Molecular Weight | 160.10 |
Target: | NF-κB |
Solubility | >7.1mg/mL in DMSO |
Purity | ≥95% |
Storage | RT |
Overview of Clinical Research | Originator: Catabasis Pharmaceuticals<br /> Developer: Catabasis Pharmaceuticals; Sarepta Therapeutics<br /> Class: Amides; Anti-inflammatories; Antihyperglycaemics; Docosahexaenoic acids; Drug conjugates; Non-opioid analgesics; Salicylates; Small molecules<br /> Mechanism of Action: NF-kappa B inhibitors<br /> Orphan Drug Status: Yes – Duchenne muscular dystrophy<br /> New Molecular Entity: Yes |
Computed Descriptor
IUPAC Name | sodium;2-hydroxybenzoate |
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InChI | InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1 |
InChIKey | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |