Metoprolol Tartrate

  • CAT Number: A000490
  • CAS Number: 56392-17-7
  • Molecular Formula: C34H56N2O12
  • Molecular Weight: 684.81
  • Purity: ≥95%
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Metoprolol Tartrate is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines.

Catalog Number A000490
CAS Number 56392-17-7
Molecular Formula

C34H56N2O12

Purity 95%
Target Adrenergic Receptor
Solubility >32.3mg/mL in DMSO
Storage -20°C
InChI 1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)
InChIKey YGULWPYYGQCFMP-UHFFFAOYSA-N
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O
Reference

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Oxandrolone, Pregabaline, and Riboflavin in SyrSpend SF pH4 Oral Suspensions. Int
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6: Allam A, Fetih G. Sublingual fast dissolving niosomal films for enhanced
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27536063; PubMed Central PMCID: PMC4977085.
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7: Wang Y, Yang M, Shen R, Shao S, Chen L, Gong W, Shan L, Gao C. Development of
metoprolol tartrate-loaded sustained-release pellets: effect of talc on the
mechanism of drug release. Pharm Dev Technol. 2016 Jul 28:1-10. doi:
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8: Monteyne T, Adriaensens P, Brouckaert D, Remon JP, Vervaet C, De Beer T.
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metoprolol tartrate in continuous twin-screw melt granulation. Int J Pharm. 2016
Oct 15;512(1):158-167. doi: 10.1016/j.ijpharm.2016.07.035. Epub 2016 Jul 21.
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9: Husain T, Shoaib MH, Yousuf RI, Maboos M, Khan M, Bashir L, Naz S. Formulation
development and comparative in vitro study of metoprolol tartrate (IR) tablets.
Pak J Pharm Sci. 2016 May;29(3):853-60. PubMed PMID: 27166530.
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10: Zhao S, Yu F, Liu N, Di Z, Yan K, Liu Y, Li Y, Zhang H, Yang Y, Yang Z, Li Z,
Mei X. Synchronous delivery of felodipine and metoprolol tartrate using
monolithic osmotic pump technology. Drug Dev Ind Pharm. 2016 Nov;42(11):1723-31.
doi: 10.3109/03639045.2016.1171332. Epub 2016 Apr 13. PubMed PMID: 27074758.

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