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Methyldiiodoarsine

Methyldiiodoarsine

  • CAT Number: R054927
  • CAS Number: 7207-97-8
  • Molecular Formula: CH3AsI2
  • Molecular Weight: 343.766
  • Purity: ≥95%
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<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Methyldiiodoarsine (CAS&nbsp;7207-97-8)&nbsp;is an arsenite metabolite in wild type CHO cells and in cells deficient in excision repair cross-complementing 1 and 2. Methyldiiodoarsine is an inhibitor of Thioredoxin reductase, an enzyme involved in the response of the cell to oxidative stress. Methyldiiodoarsine is a highly toxic compound.</span></span></span>

Catalog Number R054927
CAS Number 7207-97-8
Molecular Formula

CH3AsI2

Purity 95%
Storage Store at RT
IUPAC Name diiodo(methyl)arsane
InChI InChI=1S/CH3AsI2/c1-2(3)4/h1H3
InChIKey ZKGSUVMABCXPKK-UHFFFAOYSA-N
SMILES C[As](I)I
Reference

<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Lin, Shan, William R. Cullen, and David J. Thomas. &quot;Methylarsenicals and arsinothiols are potent inhibitors of mouse liver thioredoxin reductase.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Chemical research in toxicology</i>&nbsp;12.10 (1999): 924-930.<br />
2.Vahidnia, A., et al. &quot;Comparative toxicity of arsenite metabolites in wild type cho cells and in cells deficient in excision repair cross-complementing 1 and 2.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Toxicology in Vitro</i></span></span></span><span style="font-family: Arial, sans-serif; font-size: 13px;"><span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">&nbsp;22.6 (2008): 1662-1665.</span></span></span></span><br />
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