Methoprene

• CAT Number: I003480
• CAS Number: 40596-69-8
• Molecular Formula: C19H34O3
• Molecular Weight: 310.47
• Purity: ≥95%
• Synonyms: Methoprene; ALTOSID; Diacon; Dianex
• Solubility: 10 mM in H2O
• Storage: 3 years -20C powder
• IUPAC Name: propan-2-yl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate
• InChI: InChI=1S/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+
• InChIKey: NFGXHKASABOEEW-LDRANXPESA-N
• SMILES: CC(C)OC(=O)C=C(C)C=CCC(C)CCCC(C)(C)OC

Methoprene (CAT: I003480) is a synthetic analog of juvenile hormone (JH), a naturally occurring hormone in insects. It is widely used as an insect growth regulator (IGR) and is categorized as a biological pesticide. Methoprene does not directly kill insects but instead disrupts their life cycle by interfering with the normal progression from juvenile stages to adulthood. By mimicking the effects of JH, methoprene prevents insects from reaching maturity or reproducing, thereby effectively controlling their population. It is commonly utilized in pest control programs to target insect pests without harming non-target organisms or the environment.

Reference

1. J Am Mosq Control Assoc. 2007;23(2 Suppl):225-39. doi: 10.2987/8756971X(2007)23[225:M]2.0.CO;2.Methoprene.Henrick CA(1).

 

A brief overview is presented of the discovery and development of s-methoprene and some other juvenile hormone mimics. The identification of the natural juvenile hormones is described along with an outline of the part they play in the hormonal control of insect development. The properties and commercial applications of s-methoprene are presented with emphasis on its use in mosquito control and its minimal impact on the environment.

 

2. J Am Vet Med Assoc. 1989 Feb 1;194(3):410-2.Pharmacologic profile of methoprene, an insect growth regulator, in cattle, dogs, and cats.Garg RC(1), Donahue WA.

PMID: 2645260 [Indexed for MEDLINE]